Pengaruh Ekstrak Air Dan Etanol Kaempferia Spp. Terhadap Aktivitas Dan Kapasitas Fagositosis Sel Makrofag Yang Diinduksi Bakteri Staphylococcus Epidermidis

Ethanol 95% and water extracts of Kaempferia spp. (K. galanga, K. angustifolia, K. pandurata and K. rotunda) were tested for their influences in in-vitro phagocytosis activity and phagocytosis capacity of mouse peritoneum macrophage cells induced by Staphylococcus epidermidis. Extracts were tested at a series concentration in logarithmic order (0.1-1000) ug/ml. Imboost and distilled water were employed as positive and negative controls, respectively. The results shows that almost all extracts were capable to increase on phagocytosis activity (SPA - Screening for Phagocytosis Activity) and phagocytosis capacity (IP • Index Phagocytosis) of macrophage cells compared to positive and negative controls significantly (p<0.05). The phagocytosis activityand capacity macrophage cells were increased by increasing extract concentration. K. rotunda extracts shows reveal better on above activities in low concentration (0.1-100) ug/ml then other species. Berita Biologi Vol. 10 No. 2. Agustus 2010. P: 233-238. ISSN: 0126-1754