Badan Riset dan Inovasi Nasional
07-11-2022
12-08-2024
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Totaly eighteen kinds of endophytic fungi have been isolated from the youngstems...
Endophytic fungi have been known to produce a broad range of biologically active...
The fungus AFK-8 is one of endophytic filamentous fungus isolated from young ste...
The fungus AFK-8 is one of endophytic filamentous fungus isolated from young ste...
Thirty two endophytic fungi isolated from rhizome of six species of Zingiberacea...
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Biotransformation of Protoberberine Alkaloids by the Endophytic Fungus Coelomycetes AFKR-3 Isolated from Yellow Moonsheed Plant (Archangelisia Flava) Merr.
The endophytic fungus Coelomycetes AFKR-3 isolated from young stems of yellow moonshed plant (Archangelisia flava (L.) Merr.) has shown the capability to biotransform berberine into its 7-N-oxide derivative. Further investigations showed that the fungus can also biotransform the protoberberine alkaloid, palmatine into a new derivative palmatine 7-N-oxide in liquid medium of glucose-yeast extract-peptone. Berberine 7-N-oxide displayed the same antimicrobial activity against pathogenic bacteria and pathogenic fungi as berberineKeywords: Endophytic fungi, biotransformation, protoberberine alkaloid, 7-N-oxide derivative, antimicrobial activity Procedia Chemistry, 2014, 13, 38-43.